(A01) Supra Functional Systems in the Gas Phase

　Molecular systems in the real world, including biological systems, show their functions by synchronizing various molecular processes harmonically. This mechanism will be clarified by studying molecular systems that exhibit highly organized synchronized processes with the methodology of molecular science. We plan to investigate the structures and dynamics of supra functional systems in the gas phase by developing novel methodologies to understand the molecular functions in solution and biological systems from the viewpoint of elementary processes. This project (A01) will promote the development of new methods of vaporizing biomolecules, controlling molecular states, and performing measurements in order to elucidate the synchronized processes in real molecular systems through investigating ideal systems both experimentally and theoretically.　We are focusing our attention on the following four subjects:

TOPICS

● Theme

(1) Observation and elucidation of structures and dynamics in supra functional systems in the gas phase.
(2) Observation and elucidation of supra functional systems that connect the real and isolated systems.
(3) Development of new methods for vaporizing biomolecules.
(4) Development of new methods for controlling sates of supra functional systems in the isolated state and applications for the observation of sate-dependent phenomena.

● Keywords

gas phase spectroscopy, cluster, hydrogen-bonded network, reaction dynamics

● Research Area

cluster chemistry, excited-state dynamics, mass spectrometry, molecular spectroscopy

● Planned Research Members

Proton and charge-transfer dynamics in molecular clusters. Investigation of origin of differences between the gas phase and condensed phase

Leader Hiroshi Sekiya (Kyushu University, Professor)

Kazuhiko Ohashi (Kyushu University, Associate Professor)

Kenji Sakota (Kyushu University, Assistant Professor)

Shinkoh Nanbu (Sophia University, Professor)

Extensive hydration structure of amino acids probed by infrared spectroscopy of large-sized clusters

Leader Asuka Fujii (Tohoku University, Associate Professor)

Toshihiko Maeyama (Tohoku University, Assistant professor)

Yoshiyuki Matsuda (Tohoku University, Assistant professor)

Photoexcitation Dynamics and Elementary Process in Molecular Recognition From Cluster to Cell

Leader Masaaki Fujii (Tokyo Institute of Technology, Professor)

Makoto Sakai (Tokyo Institute of Technology, Associate Professor)

Kenro Hashimoto (Tokyo Metropolitan University, Associate Professor)

Shun-ichi Ishiuchi (Tokyo Institute of Technology, Assistant Professor)

Mitsuhiko Miyazaki (Tokyo Institute of Technology, Assistant Professor)

Kentaro Misawa (Tokyo Institute of Technology, Assistant Professor)

Measurement of organic metabolism using low-energy photons

Leader Kunio Awazu (Osaka University, Professor)

Hisanao Hazama (Osaka University, Assistant Professor)

Katsunori Ishii (Osaka University, Assistant Professor)

Development of Temperature-variable Photodissociation Spectrometer and its Application to Biological Molecules

Leader Kiyokazu Fuke (Kobe University, Professor Emeritus)

Haruki Ishikawa (Kobe University, Associate Professor)

● Proposed Research Subjects

Development of LDI Sample Plate for Soft Ionization of Bio-related Molecules and Their Ionization Mechanism

Leader Tetsu Yonezawa (Hokkaido University, Professor)

Tatsuya Kikuchi (Hokkaido University, Associate Professor)

Structure and photoreaction of biomolecule-water complexes

Leader Nobuyuki Akai (Tokyo University of Agriculture and Technology, Associate Professor)

Kazuhiko Shibuya (Tokyo Institute of Technology, Professor)

Theories of Analysis for Better Understanding on the Changes in Vibrational band Intensities and Shapes Induced by Intermolecular Interactions

Leader Hajime Torii (Shizuoka University, Professor)

Picosecond time-resolved IR-UV pump-probe spectroscopic study of the vibrational energy relaxation of benzene clusters

Leader Takayuki Ebata (Hiroshima University, Professor)

Yoshiya Inokuchi (Hiroshima University, Associate Professor)

Production of supramolecular structures of biological molecules by laser desorption and their structural characterization by IR spectroscopy

Leader Hiroyuki Saigusa (Yokohama City university, Professor)

Theoretical Analysis of Supra Biomolecular Clusters Including Nuclear Quantum and Thermal fluctuations

Leader Masanori Tachikawa (Yokohama City University, Professor)

Yukiumi Kita (Yokohama City University, Associate Professor)

Motoyuki Shiga (Japan Atomic Energy Agency, Researcher)

Toshiyuki Takayanagi (Saitama University, Professor)

Study of the hydrogen bonded structures and fluctuation for the hydrated clusters by crossed jet - IR spectroscopy

Leader Yoshiteru Matsumoto (University of Hyogo, Assistant Professor)

Spectroscopic Analysis of Specific Photochemical Reactions in an Isolated Nanospace Formed by a Well-Designed Organo-Metal Complex

Leader Yuji Furutani (Institute for Molecular Science, Associate Professor)

Makoto Fujita (The University of Tokyo, Professor)

Hideki Kandori (Nagoya Institute of Technology, Professor)

Precise Determination of Intermolecular Interactions by Utilizing Nonlinear Coherent Spectroscopy

Leader Yasuhiro Ohshima (Institute for Molecular Science, Professor)

Excited State Dynamics of Aza-substituted Nucleic Acid Bases in a Supersonic Jet

Leader Tadashi Suzuki (Aoyama Gakuin University, Professor)

Tasuku Isozaki (Aoyama Gakuin University, Assistant Professor)